This book shows the current state of research in the fields of health care and medicine, how the new technologies can be used for patient communication, health monitoring or for the treatment of patients.

Das Wiskott-Aldrich-Syndrom (WAS), ein genetisch bedingter Immundefekt mit klinischer Manifestation im Kleinkindalter, wird voraussichtlich in näherer Zukunft erstmals versuchsweise durch eine somatische Gentherapie behandelt werden. Im vor- liegenden Beitrag werden die wichtigsten medizinisch-naturwissenschaftlichen Fakten dieses Krankheitsbildes sowie die bisherigen Erfahrungen mit somatischen Gentherapien bei anderen Immunmangelsyndromen ausführlich dargestellt. Sodann erfolgt eine ethische Analyse eines möglichen gentherapeutischen Eingriffs bei WAS-Patienten, bei der die spezifischen Aspekte des Wiskott-Aldrich-Syndroms – insbesondere die fast ausschließliche Betroffenheit von Kindern sowie die unterschiedlich aussichtsreiche Alter- nativoption einer (...) allogenen Knochenmarktransplantation–wesentliche Aspekte der Beurteilung sind. Im Ergebnis zeigt sich, dass ein gentherapeutischer Eingriff im vorliegenden Fall nicht im Rahmen einer Forschungsstudie, d.h. als Humanexperiment, gerechtfertigt werden kann, sondern allein als individueller Heilversuch. Gleichwohl las- sen die besonderen Risiken und die Innovativität eines solchen Eingriffs es notwendig erscheinen, diesen Heilversuch – anders als andere Heilbehandlungen mit bislang unerprobten Mitteln – in streng kontrollierter Form durchzuführen. Der neuartige Gedanke eines kontrollierten individuellen Heilversuchs zeichnet sich daher für den vorliegenden Fall, und womöglich auch für vergleichbare risikoreiche Behandlungsansätze namentlich im Bereich der Gentherapie, als geeignetes Instrument der Konzeption und Beurteilung ab. (shrink)

Corporate social responsibility (CSR) and its action-oriented offspring Corporate Citizenship (CC) currently trigger an intensifying debate on ethics, role and behavior of companies within civil society. For companies, CSR raises the question of what may be the "good reason(s)" for acting responsible towards its members, customers or society. In order to answer this question, we face the debate on CSR and its strategic engagement drivers on the levels of corporate culture, social innovation, and civil society. In this article, we provide (...) a conceptual framework based on the analytic distinction of legitimation and sensemaking. The conceptual framework developed in this article can serve as a basis to develop a company's CSR strategy. It provides measures and instruments to make complex CSR processes more visible and manageable. (shrink)

Objective Although patients exercise greater autonomy than in the past, and shared decision making is promoted as the preferred model for doctor-patient engagement, tensions still exist in clinical practice about the primary locus of decision-making authority for complex, scarce, and resource-intensive medical therapies: patients and their surrogates, or physicians. We assessed physicians’ attitudes toward decisional authority for adult venoarterial extracorporeal membrane oxygenation (VA-ECMO), hypothesizing they would favor a medical locus. Design, Setting, Participants A survey of resident/fellow physicians and internal medicine (...) attendings at an academic medical center, May to August 2013. Measurements We used a 24-item, internet-based survey assessing physician-respondents’ demographic characteristics, knowledge, and attitudes regarding decisional authority for adult VA-ECMO. Qualitative narratives were also collected. Main Results A total of 179 physicians completed the survey (15 percent response rate); 48 percent attendings and 52 percent residents/ fellows. Only 32 percent of the respondents indicated that a surrogate’s consent should be required to discontinue VA-ECMO; 56 percent felt that physicians should have the right to discontinue VA-ECMO over a surrogate’s objection. Those who self-reported as “knowledgeable” about VA-ECMO, compared to those who did not, more frequently replied that there should not be presumed consent for VA-ECMO (47.6 percent versus 33.3 percent, p = 0.007), that physicians should have the right to discontinue VAECMO over a surrogate’s objection (76.2 percent versus 50 percent, p = 0.02) and that, given its cost, the use of VA-ECMO should be restricted (81.0 percent versus 54.4 percent, p = 0.005). Conclusions Surveyed physicians, especially those who self-reported as knowledgeable about VA-ECMO and/or were specialists in pulmonary/ critical care, favored a medical locus of decisional authority for VA-ECMO. VA-ECMO is complex, and the data may (1) reflect physicians’ hesitance to cede authority to presumably less knowledgeable patients and surrogates, (2) stem from a stewardship of resources perspective, and/or (3) point to practical efforts to avoid futility and utility disputes. Whether these results indicate a more widespread reversion to paternalism or a more circumscribed usurping of decisional authority occasioned by VA-ECMO necessitates further study. (shrink)

This document presents the Bonn PRINTEGER Consensus Statement: Working with Research Integrity—Guidance for research performing organisations. The aim of the statement is to complement existing instruments by focusing specifically on institutional responsibilities for strengthening integrity. It takes into account the daily challenges and organisational contexts of most researchers. The statement intends to make research integrity challenges recognisable from the work-floor perspective, providing concrete advice on organisational measures to strengthen integrity. The statement, which was concluded February 7th 2018, provides guidance on (...) the following key issues: § 1.Providing information about research integrity § 2.Providing education, training and mentoring § 3.Strengthening a research integrity culture § 4.Facilitating open dialogue § 5.Wise incentive management § 6.Implementing quality assurance procedures § 7.Improving the work environment and work satisfaction § 8.Increasing transparency of misconduct cases § 9.Opening up research § 10.Implementing safe and effective whistle-blowing channels § 11.Protecting the alleged perpetrators § 12.Establishing a research integrity committee and appointing an ombudsperson § 13.Making explicit the applicable standards for research integrity. (shrink)

This document presents the Bonn PRINTEGER Consensus Statement: Working with Research Integrity—Guidance for research performing organisations. The aim of the statement is to complement existing instruments by focusing specifically on institutional responsibilities for strengthening integrity. It takes into account the daily challenges and organisational contexts of most researchers. The statement intends to make research integrity challenges recognisable from the work-floor perspective, providing concrete advice on organisational measures to strengthen integrity. The statement, which was concluded February 7th 2018, provides guidance on (...) the following key issues: § 1. Providing information about research integrity§ 2. Providing education, training and mentoring§ 3. Strengthening a research integrity culture§ 4. Facilitating open dialogue§ 5. Wise incentive management§ 6. Implementing quality assurance procedures§ 7. Improving the work environment and work satisfaction§ 8. Increasing transparency of misconduct cases§ 9. Opening up research§ 10. Implementing safe and effective whistle-blowing channels§ 11. Protecting the alleged perpetrators§ 12. Establishing a research integrity committee and appointing an ombudsperson§ 13. Making explicit the applicable standards for research integrity. (shrink)

Job crafting has been established as a bottom-up work design instrument for promoting health and well-being in the workplace. In recent years, the concepts of job crafting have been applied to the university student context, proving to be positively related to student well-being. Building on person-centered analyses from the employment context, we assessed approach study crafting strategy combinations and the relationships to students’ exhaustion, study engagement, and general well-being. Data from 2,882 German university students were examined, collected online during the (...) summer term in 2020. Using latent profile analysis, we found five distinct crafting groups, which showed discriminate validity with regard to emotional exhaustion, engagement, and well-being. The results underscore the positive role of study crafting for students’ health and well-being. They further indicate a less important role of increasing social resources for emotional exhaustion when combined with a moderate increase in structural resources and a moderate increase in challenging demands. Our findings imply that interventions to promote study crafting should be considered to promote student health and well-being. (shrink)

Nietzsche's use of metaphor has been widely noted but rarely focused to explore specific images in great detail. A Nietzschean Bestiary gathers essays devoted to the most notorious and celebrated beasts in Nietzsche's work. The essays illustrate Nietzsche's ample use of animal imagery, and link it to the dual philosophical purposes of recovering and revivifying human animality, which plays a significant role in his call for de-deifying nature.

Thomas von Aquin wird weithin als einer der wichtigsten theoretischen Vordenker der kirchlichen Magielehre und damit der Hexenverfolgungen angesehen. Der Autor dieses Buches, Benediktiner in der Abtei Sankt Bonifaz in München, stellt nun die Magiologie des Aquinaten zum ersten Mal seit geraumer Zeit in umfassender Weise und auf dem neuesten Stand der theologischen und philosophischen Forschung dar. Er geht auf die naturphilosophischen Voraussetzungen dieser Magiologie ebenso ein wie auf die Überlegungen des Augustinus von Hippo, der wichtigsten Autorität für die (...) gesamte scholastische Lehre von der Magie. Thomas Linsenmann gelingt der Nachweis, daß sich Autoren vom Schlage eines Heinrich Institoris, des Verfassers des "Hexenhammers", zu Unrecht auf die theologische Autorität des heiligen Thomas berufen haben. (shrink)

ABSTRACT:Thomas Donaldson’s framework for dealing with value-conflicts between a manager’s home and host country distinguishes between a “conflict of relative [economic] development”—conflicting norms that arise because home and host are at two different stages of economic development—and a “conflict of culture,” which arises because the home and host’s different cultures generate conflicting norms on the issue the manager faces. My question here is a thought experiment. What different insights might emerge if we flipped Donaldson’s framework around? Specifically: What if (...) we viewed the kinds of conflicts that fall under Donaldson’s “conflicts of culture” as arising not because the home and host exhibit a “fundamental” conflict in cultural norms, but because they are at two different stages ofculturaldevelopment? And what if we viewed “conflicts of relative economic development” as conflicts that occur not because home and host are at two different stages of economic development but, simply, because their economies contemporaneously interact with each other in ways that generate normative conflict: call them “conflicts of economy”? (shrink)

Heinrich Beck ist Jahrgang 1929, als o. Professor Inhaber des Lehrstuhls Philosophie I an der Otto-Friedrich-Universität Bamberg bis 1997, Titular- und Honorarprofessor an sechs weiteren Universitäten in Europa und in Amerika, Dr. h.c. in Buenos Aires, Mitglied der Europäischen Akademie der Wissenschaften und Künste, Korrespondierendes Mitglied der Königlichen Spanischen Akademie der Wissenschaften, Träger des deutschen Bundesverdienstkreuzes. Zentrum und Schlüssel seines philosophischen Denkens ist eine trinitarische Ontologie, die vor allem von Thomas von Aquin und Hegel inspiriert und zum christlichen (...) Glauben hin offen ist. Die von ihm in systematischen Analysen immer wieder aufgedeckte 3-gliedrige Bewegungsstruktur der Wirklichkeit unterscheidet und verbindet die einzelnen Bereiche des Seins. So gelangt er zu einer Seinsauffassung, die weder absoluten Monismus noch absoluten Pluralismus besagt, sondern vielmehr ein Mittleres zwischen beiden begründet, nämlich eine gestufte Ähnlichkeit (Analogie) in Wechselbeziehung und Auseinandersetzung (Dialog). Damit versucht er, zur Bewältigung von zentralen Problemen und Herausforderungen der aktuellen philosophischen Diskussion beizutragen. In diesen Zusammenhang fällt auch sein langjähriges, in weltweiter Zusammenarbeit betriebenes Forschungsprojekt: «Kreativer Friede durch Begegnung der Weltkulturen», das er durch die Erfahrung zahlreicher Forschungs- und Vortragsreisen konkretisiert hat; er gilt heute als einer der Begründer und Nestoren der interkulturellen Philosophie. Der vorliegende Band will durch die Auswahl von 30 Aufsätzen einen repräsentativen Überblick über seine akademische Lehr- und Forschungstätigkeit vermitteln. Dabei soll die Vielfalt seiner Arbeitsbereiche zum Ausdruck kommen. Sie sind hier nach drei thematischen Blöcken geordnet: 1. Erziehungsphilosophie und Anthropologie, 2. Erkenntnistheorie, Ontologie, Metaphysik und Religionsphilosophie und 3. Ethik, Geschichts- und Kulturphilosophie. (shrink)

This paper is about the semantic analysis of referentially opaque verbs like seek and owe that give rise to nonspecific readings. It is argued that Montague's categorization (based on earlier work by Quine) of opaque verbs as properties of quantifiers runs into two serious difficulties: the first problem is that it does not work with opaque verbs like resemble that resist any lexical decomposition of the seek ap try to find kind; the second one is that it wrongly predicts de (...) dicto (i.e. narrow scope) readings due to quantified noun phrases in the object positions of such verbs. It is shown that both difficulties can be overcome by an analysis of opaque verbs as operating on properties. This is a strongly modified version of a paper entitled lsquoDo We Bear Attitudes towards Quantifiers?rsquo that I have presented at conferences in Gosen (Gesellschaft für Sprachwissenschaft), Ithaca (SALT I), and Konstanz (Lexikon). I owe a special debt to Hans Kamp and Arnim von Stechow for shaping my views on the subject of this paper during the past ten years or so. Comments from and discussions with the following friends and colleagues have also led to considerable improvements: Heinrich Beck, Steve Berman, David Dowty, Veerle van Geenhoven, Fritz Hamm, Irene Heim, Wolfgang Klein, Angelika Kratzer, Michael Morreau, Barbara Partee, Mats Rooth, Roger Schwarzschild, Wolfgang Sternefeld, Emil Weydert, Henk Zeevat, and three referees. (shrink)

For two decades the German edition of this book has been a standard reference point for students of the philosophy of the social sciences in Germany. Today it still stands as a unique and masterful guide to the major problems and possibilities in this field.On the Logic of the Social Sciences foreshadowed the direction in which methodological discussions have traveled since it appeared and anticipated the problems they presently face. Habermas's statement of the principal issues is concise and elegant, and (...) his own original resolution of them is of continuing relevance. He considers the main lines of thought pursued by epistemologists and methodologists of the social sciences, from neo-Kantianism to behaviorism, and from problems of measurement to those of interpretive logic, in a sustained and provocative argument that involves analysis and critique at every point and ends with his own sharply profiled position.Beginning with the turn of the century debates on the distinction between natural and cultural sciences, Habermas discusses the relationship between sociology and history. He takes up the problem of a general theory of social action, focusing first on the nature of "interpretive understanding" and then on the scope and limits of functionalist explanation. In the concluding sections, he draws on psychoanalysis and classical social theory to sketch the outlines of his view of sociology as a critical theory of the present. Along the way he provides a great deal of material that is useful in understanding his own work.Jürgen Habermas is Professor of Philosophy at the University of Frankfurt. On the Logic of the Social Sciences is included in the series Studies in Contemporary German Social Thought, edited by Thomas McCarthy. (shrink)

In the years around 1900 one of the most significant practical consequences of new styles of bacteriological thought and practice was the development of preventive vaccines and therapeutic sera. Historical scholarship has highlighted how approaches rooted in the laboratory methods of Robert Koch, Louis Pasteur and their collaborators were transformed in local contexts and applied in diverse ways to enable more effective disease identification, prevention and treatment. Amongst these, the anti-anthrax serum developed by the Italian physician Achille Sclavo (1861–1930) has (...) received little to no attention from historians. This article positions Sclavo's serum as a neglected but significant presence in British microbiology, which achieved widespread uptake amidst a wave of optimism, despite prolonged uncertainty about its mechanism of action and dosage. After being introduced to Britain in 1904 by the enterprising first medical inspector of factories Thomas Morison Legge, within a matter of months the serum became regarded by medical practitioners as an effective treatment of cutaneous anthrax, though access to ‘fresh’ serum and the necessary speedy diagnosis remained problematic. Like the disease anthrax itself, discussion of ‘Sclavo's serum’ was out of all proportion to the relatively low number of cases, reflecting a deep-seated fascination with the wider possibilities afforded by effective serum therapy. (shrink)

In an engaging and provocative paper, Linda Trevino and Gary Weaver spell out the differences between the methodological approach characteristic of the natural sciences on the one hand and that of normative inquiry on the other (Trevino and Weaver, 1991). Near the end of their paper they raise a haunting question that will have increasing significance as the management literature in ethics evolves: namely, “Can the two approaches be integrated?”As C. P. Snow (1962) noted, no one can deny either the (...) stark differences between the two worlds of normative and empirical inquiry, or the mutual suspicion shown by their inhabitants. The methodology of natural science implies a non-normative, thoroughly descriptive vision of the world in which reality awaits discovery by the scientist prepared to use increasingly sophisticated techniques. In contrast, the methodology of normative inquiry, i.e., that of traditional moral philosophy, implies a world-vision in which most important issues are allocated to ethics, where empirical pursuits are frequently trivial and always require ethical guidance, and where empirical theories contain normative presuppositions unrecognized as normative even by their scientific adherents. (shrink)

Die im Dialektik-Buch aufgezeigten 16 Quell-Typen von Dialektik werden auf das große Thema Liebe angewandt, woraus sich ebenso viele differenzierte Antworten auf die Frage ergeben, ob denn Liebe logisch sein könne. Die dialogische Denkströmung im 19. Und 20. Jahrhundert (Jacobi, Hölderlin, Feuerbach, Buber, Ebner, Rosenzweig, Marcel usw.) war nur teilweise im Recht mit ihrer schroffen Opposition gegen die Subjekt-Objekt-Dialektik Kants und Hegels. Dialektik wie Dialogik sind beide Denken in Relationen und Gegensätzen. Auf der sehr innovativen Grundlage seiner kürzlich entwickelten Typen (...) von Dialektik legt Heinrichs eine dialogische Dialektik dar, die zugleich dialektische Dialogik ist. Der bisher unfruchtbare Gegensatz zwischen liebevoller Zwischenmenschlichkeit und logischer Schärfe wird fruchtbar gemacht, auch durch starkes Eingehen auf Hegels Jugendfreund und Mit-Jubilar Hölderlin Das Buch enthält im 1. Teil frühere Arbeiten des Verfassers, die in prominenten Sammelwerken verstreut waren, während der 2. Teil das innovative Niveau des Dialektik-Buches in überraschender Weise hält, ja steigert. (shrink)

Als "Flow" bezeichnet die Psychologie die beglückende Erfahrung, selbstvergessen in einer Tätigkeit aufzugehen und auf diese Weise in Fluss zu geraten. Während das Flow-Erlebnis auf psychologischer Seite seit einigen Jahrzehnten analysiert und diskutiert wird, steht in der Philosophie eine eingehende Erörterung des Phänomens bislang aus. Schmaus erschließt diese Erfahrung erstmals für das philosophische Gespräch, arbeitet ihre Grundzüge heraus und untersucht mögliche Schlussfolgerungen für unser Verständnis von Wirklichkeit. Dazu widmet er sich der Philosophie Heinrich Rombachs (1923-2004) und öffnet sie damit (...) zugleich einem neuen Zugang. Das "reine Geschehen", das in Rombachs Strukturphilosophie eine zentrale Rolle spielt, und die "hermetische Erfahrung", die seiner philosophischen Hermetik zugrundeliegt, verweisen beide auf das Flow-Erleben. Dieses kann daher als Grunderfahrung seines Denkens verstanden werden. (shrink)

Excerpt from Die Psychologie des Hugo von St. Viktor: Ein Beitrag zur Geschichte der Psychologie in der Fruhscholastik Wirksamkeit, zum Kloster St. Viktor in Paris. Als Lehrer schon an der Seite des Priors Thomas tatig (seit wurde er nach dessen Tode sein Nachfolger in der Leitung der Schule. Er starb am 11. Februar 1141 im Alter von 44 Jahren. 1) About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book (...) is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works. (shrink)

In _My Father's House_, the political philosopher Thomas Dumm explores a series of stark and melancholy paintings by the American artist Will Barnet. Responding to the physical and mental decline of his sister Eva, who lived alone in the family home in Beverly, Massachusetts, Barnet began work in 1990 on what became a series of nine paintings depicting Eva and other family members, as they once were and as they figured in the artist's memory. Rendered in Barnet's signature (...) quiet, abstract style, the paintings, each featured in full color, present the ordinary and extraordinary aspects of a twentieth-century American family. Dumm first became acquainted with Barnet and his paintings in 2008. Given his scholarly focus on the lives of ordinary people, he was immediately attracted to the artist's work. When they met, Dumm and Barnet began a friendship and dialogue that lasted until the painter's death in 2012, at the age of 101. This book reflects the many discussions the two had concerning the series of paintings, Barnet's family, his early life in Beverly, and his eighty-year career as a prominent New York artist. Reading the almost gothic paintings in conversation with the writers and thinkers key to both his and Barnet's thinking—Emerson, Spinoza, Dickinson, Benjamin, Cavell, Nietzsche, Melville—Dumm's haunting meditations evoke broader reflections on family, mortality, the uncanny, and the loss that comes with remembrance. (shrink)

Wie ist der Freiwillige Verzicht auf Essen und Trinken und eine medizinische Begleitung dabei ethisch zu bewerten? Die ethische Bewertung des Freiwilligen Verzichts auf Essen und Trinken stellt Patienten und Angehörige, aber auch begleitende Ärzte und Pflegende vor erhebliche Schwierigkeiten. Basierend auf Ergebnissen eigener qualitativer Interviews mit Personen nach dem FVET ihrer Angehörigen legt dieser Artikel die bestehende Unklarheit und inhärente ethische Ambivalenz des Begriffs FVET frei, stellt aber in der Unterscheidung von FVET-Fällen – mit bzw. ohne terminale Erkrankung – (...) einen Weg zur Lösung der Frage nach der ethischen Bewertung des „Sterbefastens“ und seiner medizinischen Begleitung vor: Ethisch wird der Freiwillige Verzicht auf Essen und Trinken und seine medizinische Begleitung erst in der Analyse von Situation und Intention der Handelnden beurteilbar. Ausgehend vom Konzept eines frei gewollten Verzichts auf Essen und Trinken bei einsichts- und einwilligungsfähigen Personen mit dem Bewusstsein, damit ihr Leben zu verkürzen oder zu beenden, wird mit der Philosophie Thomas von Aquins argumentiert, dass eine ethische Bewertung die Begleitumstände und beabsichtigten Ziele miteinschließen muss, ebenso wie die Auswirkungen auf Angehörige und die Implikationen von und für ein Behandlungsteam. (shrink)

ABSTRACT:The articles in the special issue ofBusiness Ethics Quarterly, “Normative Business Ethics in a Global Economy: New Directions on Donaldsonian Themes,” were written by a set of outstanding scholars: Margaret M. Blair, Joseph P. Gaspar, Nien-hê Hsieh, Peter L. Jennings, Marietta Peytcheva, Andreas Georg Scherer, Amy J. Sepinwall, Andrew Stark, Danielle E. Warren, and Manuel Velasquez. In this commentary I reply to my colleagues, arranging my reply around the following themes: 1) the corporate moral agent; 2) the idea of (...) a social contract for business; 3) managing ethics within corporations; and 4) values in business. I discuss each in turn. However, I reflect first on my idiosyncratic approach to business ethics. (shrink)

This issue includes a number of papers on reproductive ethics, broadly construed. In a recent book, Anja Karnein proposed that embryos created in vitro should be offered up for adoption before being discarded or used in research;1 here Timothy Murphy offers a critical response . Elsewhere, Tak Chan and Stark & Delatycki debate the role of medical professionals in providing parentage determination. Chan argues that doctors are obliged to provide parentage tests when this is requested by parents, provided there (...) is a low risk that the child will be abandoned . Stark & Delatycki discuss some difficulties raised by the ‘risk of abandonment’ condition . Finally, papers by Kate Greasley and David Lang discuss the controversy surrounding the criminal prosecution of abortion doctor Kermit Gosnell. Greasley criticises the way in which some commentators capitalised on horror at Gosnell's extreme practices to advance more general anti-abortion objectives . Lang argues, against Greasley, that the dominant pro-life response to the case was neither self-contradictory nor intellectually dishonest .The issue is dominated, however, by discussions of ‘bioenhancement’ – the use of biomedical technologies to augment human capacities. A common criticism of bioenhancements is that they are anti-social: though they may benefit the user, they will have a negative effect on society-at-large. Such concerns are perhaps well placed in relation to the most obvious contemporary examples of bioenhancement: doping in sport, aesthetic medicine, and the use of stimulants to enhance examination performance. However, two varieties of bioenhancement discussed in this issue might be thought to have more positive social effects.David Shaw discusses the possible use of cognitive enhancing drugs to improve health outcomes in disadvantaged segments of society . Such enhancements might be thought to have desirable social …. (shrink)